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Overall, high monounsaturated fat diets increase HDL cholesterol concentrations without adversely affecting LDL cholesterol concentrations. High monounsaturated fat diets may also reduce the susceptibility of LDL particles to oxidation and therefore reduce their atherogenic potential. Furthermore, a high monounsaturated fat diet should not induce weight gain in patients provided that energy intake is controlled. Therefore, this dietary approach can be recommended to type 2 diabetes patients who are trying to maintain or lose weight (Garg, 1998; Gumbiner et al, 1998).

The results of a case-control study (Linos et al, 1999) confirms the finding of a previous study in Greece, which showed that risk of rheumatoid arthritis (RA) is inversely associated with consumption of olive oil. Moreover, this study extend these observations by showing that lifelong consumption of olive oil and consumption of cooked vegetables is independently associated with risk of developing RA. There is a strong possibility that this protective effect is attributed to the relatively high unsaturated fatty acid content of olive oil. The dietary benefits of olive oil may also be attributed, at least in part, to the presence of natural antioxidants.

This study showed that lifelong consumption of olive oil and consumption of cooked vegetables is independently associated with risk of developing rheumatoid arthritis.

A study develop by Serrano, et al (1997) provides evidence in man that a 30-day period of diets containing olive oil, a source of dietary lipids with the highest proportion of oleic acid, results in attenuated gastric acid secretion in response to a liquid meal when compared with those containing sunflower oil, a fat high in polyunsaturated fatty acid content. This was indicated by the slower drop in intragastric pH after the ingestion of the meal.

Solfrizzi et al. (1999) studied the relationships between dietary macronutrient intakes and age related changes in cognitive functions. They investigated these associations in the prevalence survey (1992 through 1993) of the Italian Longitudinal Study on Aging. The population-based sample was 5,632 subjects, ages 65 to 84 years. There was an inverse relationship between monounsaturated fatty acids energy intake and cognitive decline. They concluded that in an elderly population of Southern Italy with a typical Mediterranean diet, high monounsaturated fatty acids intake appeared to be protective against age-related cognitive decline.

References

Garg, A. High-monounsaturated-fat diets for patients with diabetes mellitus: a meta-analysis. American Journal of Clinical Nutrition, Vol. 67(suppl): 577S-582S, 1998.

Griffin M. E., et al. Non-insulin dependent diabetes mellitus: dietary monounsaturated fatty acids and low-density lipoprotein composition and function. Quarterly Journal of Medicine, Vol. 89: 211-216, 1996.

Gumbiner B., et al. Effects of a Monounsaturated fatty Acid-Enriched Hypocaloric Diet on cardiovascular Risk factors in Obese Patients with Type 2 Diabetes. Diabetes Care, Vol. 21, Number 1, January 1998.

Hu F., et al. Dietary fat intake and the risk of coronary heart disease in women. The New England Journal of Medicine. Vol. 337, pages 1491-1499, 1997. Keys A., et al. The diet and 15-year death rate in the Seven Countries Study. American Journal of Epidemiology. Vol. 124, pages 903-915, 1986.

Lahoz C., et al. Las dietas enriquecidas en ácidos grasos monoinsaturados y ácidos grasos poliinsaturados omega-3 disminuyen la presión arterial, sin modificar la concentración de insulina plasmática en sujetos sanos. Medicina Clínica (Barcelona). Vol. 112, pages 133-137, 1999.

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